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Vitamin B5 (pantethine) appears to reduce the hypersecretion of cortisol when under high stress. If you’re under prolonged stress, take 500 mg/day. Since Vitamin B5 is water soluble, any excess will be excreted in your urine.
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Vitamin C, another water soluble vitamin has been shown to lower cortisol levels and is another safe vitamin to use. Recommended dosage is 1,000 mg three times per day. If you notice you’ve developed loose stools, although not likely at this level, lower your dose to perhaps 1,000 mg twice per day.
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Phosphatidylserine (PS) …. Yes, I know it’s a mouthful … I still can’t pronounce it properly J. This supplement is an extract from the membrane of a cell, and has been shown to reduce cortisol levels when taken in pill form. Optimal dose appears to be 400 to 800 mg/day. PS has been shown to buffer stress-related rises in cortisol and improves mood under stress. It even improves memory!!!
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Fish oil has been shown to lower cortisol levels due to mental stress along with lowering blood pressure. It’s important to choose a form of fish oil that has been third-party tested and free of mercury and other endocrine disruptors. 4 grams of fish oil per day has been shown to reduce morning cortisol levels (very important) and increase lean body mass.
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L-tyrosine is an amino acid that serves as a precursor to the neurotransmitters norepinephrine and dopamine which can be depleted by stress. Just don’t take it right before bed as this can interfere with sleep.
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Asian ginseng helps regulate high cortisol levels, reduce fatigue and stress and improves immune function. It has also been shown to help lower blood sugar, improve cognition, working memory and calmness.
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Korean red ginseng helps women with symptoms of menopause such as fatigue, insomnia, depression and anxiety. It has also been used as a sexual tonic.
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Ashwagandha may help reduce anxiety and buffers effects of high stress. Ashwagandha is less sedating than other ginsengs which is excellent for women with anxiety and/or sleep issues. Fortunately Ashwagandha is safely used with antidepressants, but please check with your pharmacist.
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Relora is an herbal combination that may reduce evening cortisol and stress-related eating, but only in overweight and obese women. Relora may also reduce anxiety in premenopausal women.
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Rhodiola is used to enhance physical and mental performance, stimulate the nervous system, fight depression and improve sleep. It seems to alter levels of dopamine, norepinephrine and serotonin in the brain. It has also shown to improve mental performance and concentration and decrease cortisol levels.
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Vitamin B complex (50 mg twice a day) together with 1,000 mg Vitamin C three times per day helps to restore cortisol production and diurnal rhythm (sleep/wake cycle).
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Licorice (Glycyrrhiza) … and no, I’m not talking about the red chewy candy although it is kinda yummy … helps raise cortisol production. Major cautions here. If you are pregnant or planning to become pregnant soon, I would recommend you skip the licorice. Also, if you have high blood pressure, skip the licorice or if it’s not too high, consider deglycyrrhizinated licorice. Just try a bit, keep an eye on your blood pressure and you can try a bit more. But please check with your pharmacist.
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Grapefruit juice has been shown in some cases to raise serum cortisol so the same cautions should be applied to licorice as well.